Recent research into the underlying mechanisms and immune dysfunction that lead to chronic inflammation and pain in psoriatic arthritis (PsA) has led to significant improvements in the care of patients and the development of novel treatment options. The RELIEF initiative is an online learning tool for clinicians and patients interested in the management of PsA. By compiling up-to-date information on the presentation, prognosis, and treatment options for PsA, we aim to provide users with a convenient resource that improves clinical outcomes and the quality of life for patients. Our Clinical Care Toolkit is designed to empower healthcare providers to personalize therapy based on therapeutic response and incorporate patient-specific factors into treatment decisions. Our Patient Toolkit is a handy resource that educates patients about their disease and empowers them to engage in their healthcare decisions.